White Paper: Measuring the Neutrino Mass Hierarchy

This white paper is a condensation of a report by a committee appointed jointly by the Nuclear Science and Physics Divisions at Lawrence Berkeley National Laboratory (LBNL). The goal of this study was to identify the most promising technique(s) for resolving the neutrino mass hierarchy. For the most part, we have relied on calculations and simulations presented by the proponents of the various experiments. We have included evaluations of the opportunities and challenges for these experiments based on what is available already in the literature.Comment: White paper prepared for Snowmass-201

Radon mitigation during the installation of the CUORE 0νββ0\nu\beta\beta decay detector

CUORE - the Cryogenic Underground Observatory for Rare Events - is an experiment searching for the neutrinoless double-beta ($0\nu\beta\beta$) decay of $^{130}$Te with an array of 988 TeO$_2$ crystals operated as bolometers at $\sim$10 mK in a large dilution refrigerator. With this detector, we aim for a $^{130}$Te $0\nu\beta\beta$ decay half-life sensitivity of $9\times10^{25}$ y with 5 y of live time, and a background index of $\lesssim 10^{-2}$ counts/keV/kg/y. Making an effort to maintain radiopurity by minimizing the bolometers' exposure to radon gas during their installation in the cryostat, we perform all operations inside a dedicated cleanroom environment with a controlled radon-reduced atmosphere. In this paper, we discuss the design and performance of the CUORE Radon Abatement System and cleanroom, as well as a system to monitor the radon level in real time.Comment: 10 pages, 6 figures, 1 tabl

Opportunities and Challenges for Error Correction Scheme for Wireless Body Area Network: A Survey

This paper offers a review of different types of Error Correction Scheme (ECS) used in communication systems in general, which is followed by a summary of the IEEE standard for Wireless Body Area Network (WBAN). The possible types of channels and network models for WBAN are presented that are crucial to the design and implementation of ECS. Following that, a literature review on the proposed ECSs for WBAN is conducted based on different aspects. One aspect of the review is to examine what type of parameters are considered during the research work. The second aspect of the review is to analyse how the reliability is measured and whether the research works consider the different types of reliability and delay requirement for different data types or not. The review indicates that the current literatures do not utilize the constraints that are faced by WBAN nodes during ECS design. Subsequently, we put forward future research challenges and opportunities on ECS design and the implementation for WBAN when considering computational complexity and the energy-constrained nature of nodes

Effects of 2.45 GHz Wi‐Fi exposure on sleep‐dependent memory consolidation

Studies have reported that exposure to radiofrequency electromagnetic fields (RF-EMF) emitted by mobile telephony might affect specific sleep features. Possible effects of RF-EMF emitted by Wi-Fi networks on sleep-dependent memory consolidation processes have not been investigated so far. The present study explored the impact of an all-night Wi-Fi (2.45 GHz) exposure on sleep-dependent memory consolidation and its associated physiological correlates. Thirty young males (mean ± standard deviation [SD]: 24.1 ± 2.9 years) participated in this double-blind, randomized, sham-controlled crossover study. Participants spent five nights in the laboratory. The first night was an adaptation/screening night. The second and fourth nights were baseline nights, each followed consecutively by an experimental night with either Wi-Fi (maximum: psSAR10g = <25 mW/kg; 6 min average: <6.4 mW/kg) or sham exposure. Declarative, emotional and procedural memory performances were measured using a word pair, a sequential finger tapping and a face recognition task, respectively. Furthermore, learning-associated brain activity parameters (power spectra for slow oscillations and in the spindle frequency range) were analysed. Although emotional and procedural memory were not affected by RF-EMF exposure, overnight improvement in the declarative task was significantly better in the Wi-Fi condition. However, none of the post-learning sleep-specific parameters was affected by exposure. Thus, the significant effect of Wi-Fi exposure on declarative memory observed at the behavioural level was not supported by results at the physiological level. Due to these inconsistencies, this result could also be a random finding

Health and financial burden of adverse childhood experiences in England and Wales: a combined primary data study of five surveys

Objective To estimate the health and financial burden of adverse childhood experiences (ACEs) in England and Wales. Design The study combined data from five randomly stratified cross-sectional ACE studies. Population attributable fractions (PAFs) were calculated for major health risks and causes of ill health and applied to disability adjusted life years (DALYs), with financial costs estimated using a modified human capital method. Setting Households in England and Wales. Participants 15 285 residents aged 18-69. Outcome measures The outcome measures were PAFs for single (1 ACE) and multiple (2-3 and ≥4 ACEs) ACE exposure categories for four health risks (smoking, alcohol use, drug use, high body mass index) and nine causes of ill health (cancer, type 2 diabetes, heart disease, respiratory disease, stroke, violence, anxiety, depression, other mental illness); and annual estimated DALYs and financial costs attributable to ACEs. Results Cumulative relationships were found between ACEs and risks of all outcomes. For health risks, PAFs for ACEs were highest for drug use (Wales 58.8%, England 52.6%), although ACE-attributable smoking had the highest estimated costs (England and Wales, £7.8 billion). For causes of ill health, PAFs for ACEs were highest for violence (Wales 48.9%, England 43.4%) and mental illness (ranging from 29.1% for anxiety in England to 49.7% for other mental illness in Wales). The greatest ACE-attributable costs were for mental illness (anxiety, depression and other mental illness; England and Wales, £11.2 billion) and cancer (£7.9 billion). Across all outcomes, the total annual ACE-attributable cost was estimated at £42.8 billion. The majority of costs related to exposures to multiple rather than a single ACE (ranging from 71.9% for high body mass index to 98.3% for cancer). Conclusions ACEs impose a substantial societal burden in England and Wales. Policies and practices that prevent ACEs, build resilience and develop trauma-informed services are needed to reduce burden of disease and avoidable service use and financial costs across health and other sectors

Galileo imaging results from the second Earth-Moon flyby: Lunar Maria and related units

The second flyby of the Earth-Moon System by Galileo occurred on December 7, 1992, on its trajectory toward Jupiter. The flyby took the spacecraft over the lunar north polar region from the dark farside and continued across the illuminated nearside. This provided the first opportunity to observe northern and northeastern limb regions with a modern, multispectral imaging system with high spatial resolution (up to 1.1 km/pixel). Scientific objectives included compositional assessment of previously uncharacterized mare regions, study of various light plains materials, and assessment of dark mantle deposits (DMD) and dark halo craters (DHC). Color composite images were prepared from ratios of Galileo SSI filter data (0.76/0.41 yields red; 0.76/0.99 yields green; 0.41/0.76 yields blue) and used for preliminary comparison of units. The 0.41/0.76 ratio has been empirically correlated to Ti content of mare soils (blue is relatively high, red is relatively low). The relative strengths of the ferrous one micron absorption in mafic minerals can be compared using the 0.76/0.99 ratio. In addition, relative ages of units analyzed spectrally were determined from crater statistics using Lunar Orbiter images following the techniques of Neukum et al. Mare deposits analyzed include Mare Humboldtianum, central and eastern Mare Frigoris, Mare Crisium and other deposits in the Crisium Basin, and isolated mare patches on the northeastern lunar limb. Preliminary results show a diversity of 0.41/0.76 micron signatures, implying a wide range of titanium contents. Some light plains units are similar to units found at the Apollo 16 site; others may be ancient mare materials. Dark mantle deposits (DMD) analyzed also are available

Closed-loop Stimulation of Temporal Cortex Rescues Functional Networks and Improves Memory

Memory failures are frustrating and often the result of ineffective encoding. One approach to improving memory outcomes is through direct modulation of brain activity with electrical stimulation. Previous efforts, however, have reported inconsistent effects when using open-loop stimulation and often target the hippocampus and medial temporal lobes. Here we use a closed-loop system to monitor and decode neural activity from direct brain recordings in humans. We apply targeted stimulation to lateral temporal cortex and report that this stimulation rescues periods of poor memory encoding. This system also improves later recall, revealing that the lateral temporal cortex is a reliable target for memory enhancement. Taken together, our results suggest that such systems may provide a therapeutic approach for treating memory dysfunction

Search for extraterrestrial antineutrino sources with the KamLAND detector

We present the results of a search for extraterrestrial electron antineutrinos ($\bar{\nu}_{e}$'s) in the energy range $8.3 MeV < E_{\bar{\nu}_{e}} < 31.8 MeV$ using the KamLAND detector. In an exposure of 4.53 kton-year, we identify 25 candidate events. All of the candidate events can be attributed to background, most importantly neutral current atmospheric neutrino interactions, setting an upper limit on the probability of $^{8}$B solar $\nu_{e}$'s converting into $\bar{\nu}_{e}$'s at $5.3 \times 10^{-5}$ (90% C.L.), if we assume an undistorted $\bar{\nu}_{e}$ shape. This limit corresponds to a solar $\bar{\nu}_{e}$ flux of $93 cm^{-2} s^{-1}$ or an event rate of $1.6 events (kton-year)^{-1}$ above the energy threshold $(E_{\bar{\nu}_{e}} > 8.3 MeV)$. The present data also allows us to set more stringent limits on the diffuse supernova neutrino flux and on the annihilation rates for light dark matter particles.Comment: 22 pages, 6 figure

Cost of health inequality to the NHS in Wales

Background: Forty years from the seminal work of Welsh GP Julian Tudor Hart on the Inverse Care Law, inequalities in health and healthcare remain deeply embedded in Wales. There is a wider gap (over 17 years) in healthy life expectancy between people living in the most and least deprived neighborhoods in Wales. This health inequality is reflected in additional healthcare use. In this study we estimate the cost of inequality associated with this additional healthcare use to the publicly funded National Health Service (NHS) in Wales. Methods: We retrieved administrative data on all NHS inpatient admissions, outpatient and accident and emergency attendances in Wales between April 2018 and March 2019 from Digital Health and Care Wales (DHCW). Hospital service use data were translated to costs using Healthcare Resource Group (HRG) and health service specific unit cost data and linked with area level mid-year population and deprivation indices in order to calculate the healthcare costs associated with socioeconomics deprivation. Results: Inequality in healthcare use between people from more and less deprived neighborhoods was associated with an additional cost of £322 million per year to the NHS in Wales, accounting for 8.7% of total NHS hospital expenditure in the country. Emergency inpatient admissions made up by far the largest component of this additional cost contributing £247.4 million, 77% of the total. There are also substantial costs of inequality for A&E attendances and outpatient visits, though not maternity services. Elective admissions overall have a negative cost of inequality, since among men aged 50–75 and women aged 60–70, elective utilization is actually negatively associated with deprivation. Conclusion: There are wide inequalities in health and healthcare use between people living in more deprived neighborhoods and those living in less deprived neighborhoods in Wales. Tackling health inequality through a combination of health promotion and early intervention policies targeted toward deprived communities could yield substantial improvement in health and wellbeing, as well as savings for the Welsh NHS through reduced use of emergency hospital care